hhrtBase

Transcription readthrough
Under specific conditions, the transcription machinery may fail to recognize termination signals, leading to transcription extending beyond the defined gene boundaries—a phenomenon known as transcription readthrough (TRT) . This process results in the production of RNA molecules, referred to as readthrough transcripts (RT transcripts) or Downstream-of-Gene (DoG) transcripts.

Welcome to hhrtBase
hhrtBase (Heathy Human Readthrough Database) is an innovative and meticulously curated database dedicated to the exploration and analysis of transcription readthrough events in the human genome. As a cornerstone for genomic research, hhrtBase provides a robust platform for scientists, researchers, and bioinformatics professionals to access high-quality data and insights about readthrough transcription phenomena.

Why hhrtBase Matters?
Transcription readthrough events play a critical role in regulating gene expression and are linked to various physiological processes and diseases. hhrtBase bridges the gap between raw genomic data and actionable insights, empowering the scientific community to advance our understanding of these complex mechanisms. Dive into the world of human genome transcription and unlock new possibilities in genomic research with hhrtBase.